Sarcomatoid Mesothelioma is a bit all types of cancer caused by exposure to asbestos. It is difficult to diagnose sarcomatoid mesothelioma, it just responds to any type of treatment. This is the most serious of all asbestos related diseases. The possibility of finding this type of cancer is on the lips and larynx. However, in some cases, effects on the oral cavity, as well. As in all other forms of cancer mesothelioma, cancer is a deadly disease and not responding to each treatment. Although radiation therapy is recommended for the treatment of cancer tumors, but some of them can not face strahlungsempfindlichen and radiation for treatment.

Diagnosis of Sarcomatoid Mesothelioma:

Differentiating sarcomatoid mesothelioma from other tumors of the optical microscopy is difficult. The role of immunohistochemistry is not clearly defined in its diagnosis. Since sarcomatoid mesothelioma is not always negative cytokeratin, the distinction between it and the sarcoma is not always possible. In this context, the doctors involved to investigate the diagnostic utility of immunohistochemistry in distinguishing its sarcomatoid mesothelioma histologic reproduced, high-grade sarcomatoid sarcoma and lung cancer.

For their study, researchers at the dye with mesothelioma sarcomatoid components. It assesses the intensity and distribution of color with a quantity of semi-key. Only single tumor staining was considered positive for Auftabellierung. Then they compared the immunophenotypic profiles of these tumors with 24 High-Grade-sarcomas. The sarcomatoid carcinomas were stained for thyroid transcription factor-1 (TTF-1).

The study showed that cytokeratin 5 / 6 of the most dyed epithelioid, but were rarely sarcomatoid anzufärben. On the other hand, and any colored THROMBOMODULIN Calretinin 70% of sarcomatoid. All 10 were negative for TTF-1 sarcomatoid. This led to the conclusion that a wide immunophenotypic overlap between sarcomatoid. Cytokeratin and calretinin have the most benefit in the differentiation of sarcomatoid different. Clinicopathological data, especially information on the gross benefit of the tumor is very important for sarcomatoid tumors. Therefore, it should be noted with care and is correlated with microscopic findings and immunohistochemistry.

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